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Kidney removal is mainly carried out by glomerular filtration in combination with active tubular secretion. The pharmacokinetic processes of Champix do not significantly depend on status, age, sex, race, or concomitant therapy of a person.
The biotransformation of Champix is minimal: only 92% of the dose is excreted unchanged by the kidneys, less than 10% as metabolites.
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Вибачте , ви повинні увійти в систему , щоб відповісти в темі .